The papillomavirus (PV) protein E2 is one of only two proteins required for viral DNA replication. E2 is the viral transcriptional regulator/activation protein as well as the initiator of viral DNA replication. E2 is known to interact with various cellular DNA replication proteins. including the PV E1 protein. https://www.foldlyers.shop/product-category/wireless-over-ear-2/