Thermal adaptation is essential in all organisms. In yeasts. the heat shock response is commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased genetic screens with directed molecular dissection to demonstrate that multiple signalling cascades contribute to thermal adaptation in the pathogenic yeast Candida albicans. https://www.roneverhart.com/Mizuno-Prospect-GXC105-Youth-Catcher-s-Mitt/