The Principal cytochrome P450 isoenzyme concerned seems for being CYP2E1, with CYP1A2 and CYP3A4 as additional pathways. About 85% of the oral dose seems during the urine within 24 hours of administration, most since the glucuronide conjugate, with small amounts of other conjugates and unchanged drug. The drug, codeine, has https://codeine.store/product/cough-syrup-uses/
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